"Doug's Big Panic" is the 21st episode of Doug in the Disney era. It first aired on February 1, 1997, on ABC.
Guy sees a musical and is inspired by it. He tells Skeeter to work on a secret script for a huge drama play for Beebe Bluff Middle School. The play is a love story between Leonardo da Vinci and the Mona Lisa. Doug gets interested in auditioning when he learns Patti gets the female lead, and is in a kissing scene at the end of the play. Doug tries hard to get the male lead, but when Guy gives himself the role, Doug wonders if his work was wasted. But before showtime, Guy gets sick and someone else has to be the male lead. Doug now becomes the male lead filling in for Guy. Two days later, Patti gets sick after Guy has given to her the spots, and Judy takes over for her.